WebMar 8, 2024 · The preclinical data presented at ESMO TAT 2024 have been generated in collaboration with the Dutch precision medicine company, NTRC, from which Basilea in-licensed the drug candidate. Web1 day ago · In CheckMate 714, no clinical benefit with nivolumab plus ipilimumab versus nivolumab was observed in patients with tumour PD-L1 expression less than 1% or 1% or greater; however, analysis by combined positive score (CPS) was not protocol defined. Treatment effect by CPS could not be analyzed in Checkmate 714 due to lack of a …
Studies confirm the clinical potential of ATR inhibitors
WebMar 8, 2024 · ESMO TAT Congress 2024 Adding precision to dose-finding in early-phase clinical trials has become critical in the immunotherapy era, and moving away from paradigms of the past has become mandatory Dose finding is the core of drug development, setting the stage for efficacy by ensuring safety first. WebContent of this presentation is copyright and responsibility of the author. Permission is required for re-use. T ime on Study (Months) T ime on Study (Months) dj vixx
Combination of Enzalutamide Plus Abiraterone Acetate and...
WebApr 12, 2024 · The recommended intratechal dose of nivolumab is 50 mg with intravenous nivolumab 240 mg every 2 weeks. Median OS was 4.9 months, with 44% and 26% rates at 26 and 52 weeks, respectively. The authors concluded that these initial results suggest that concurrent intratechal and intravenous nivolumab is safe and feasible with potential … WebMar 7, 2024 · ESMO TAT: Tumor therapies find new ways into the brain, by finesse or force. Whether as primary tumors or metastases, brain tumors remain stubbornly intractable to … WebFeb 28, 2024 · SAN DIEGO, Feb. 28, 2024 (GLOBE NEWSWIRE) -- Cidara Therapeutics, Inc. (NASDAQ: CDTX), a biotechnology company developing long-acting therapeutics designed to help improve the standard of care for patients facing serious diseases, today announced that it will present highlights from pharmacokinetic studies of a CD73 … dj vj bubba yae