Itpr2
Web21 mrt. 2024 · GeneCards Summary for ITPR3 Gene. ITPR3 (Inositol 1,4,5-Trisphosphate Receptor Type 3) is a Protein Coding gene. Diseases associated with ITPR3 include Charcot-Marie-Tooth Disease, Demyelinating, Type 1J and Type 1 Diabetes Mellitus . Among its related pathways are Development Angiotensin activation of ERK and … Inositol 1,4,5-trisphosphate receptor, type 2, also known as ITPR2, is a protein which in humans is encoded by the ITPR2 gene. The protein encoded by this gene is both a receptor for inositol triphosphate and a calcium channel.
Itpr2
Did you know?
Web1 sep. 2024 · Abstract. Background.Previous researches indicate that Itpr2-/-mice (inositol 1,4,5-trisphosphate receptor type 2 knockout mice) show depressive-like symptoms; however, little is known regarding the in vivo neurobiological effect of Itpr2 as well as the specific pattern of brain abnormalities in Itpr2-/-mice. Methods/Materials.First, behavioral … Web2 sep. 2024 · Relative gene expression levels of ER calcium-channels (C) RYR3 and (D) ITPR2 (inositol 1,4,5-triphosphate receptor type 2) in astrocytes shown as fold change …
WebExpression of ITPR2 (CFAP48, IP3R2) in cancer tissue. The cancer tissue page shows antibody staining of the protein in 20 different cancers. We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again. ITPR2. WebITPR2: Inositol 1,4,5-trisphosphate receptor type 2; Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. This release is regulated by cAMP both dependently and independently of PKA (By similarity); Cilia and flagella associated (2701 aa)
Web12 apr. 2016 · Using inositol 1,4,5-trisphosphate receptor type 2 knockout (Itpr2(-/-)) mice to specifically disturb somatic Ca(2+) signaling in astrocytes, we showed that developmental elimination of the ventral posteromedial nucleus relay synapse was impaired. Interestingly, intracerebroventricular injection of ATP, but not adenosine, ... WebITPR2. （inositol 1,4,5-trisphosphate receptor type 2）. 该基因编码的蛋白属于肌醇1，4，5-三磷酸受体家族，其成员是细胞内第二信使钙释放通道。. 这些蛋白质介导细胞质钙的增 …
Web22 sep. 2009 · Description. An autosomal recessive disorder characterized by generalized, isolated anhidrosis, severe heat intolerance, and morphologically normal eccrine sweat …
WebITPR2 is a functional target gene of the BACH1 transcription factor according to ChIP-seq and knockdown analysis in HEK 293 cells. The result of this study suggested that ITPR2 … bus map west sussexWeb18 nov. 2024 · Major depressive disorder (MDD) is a devastating mental disorder that affects up to 17% of the population worldwide. Although brain-wide network-level abnormalities in MDD patients via resting-state functional magnetic resonance imaging (rsfMRI) exist, the mechanisms underlying these network changes are unknown, despite their immense … cbs us openWebITPR2 as a susceptibility gene in sporadic amyotrophic lateral sclerosis: a genome-wide association study. Michael A. van Es, Paul W. Van Vught, Hylke M. Blauw, ... bus marcheWeb23 jun. 2024 · Nodal marginal zone lymphoma (NMZL) is a rare B-cell neoplasm, the genetic and transcriptomic landscape of which are unclear. Using high-throughput sequencing for whole-exome and transcriptome, we investigated the genetic characteristics of NMZL in a discovery cohort (n = 8) and validated their features in an extended cohort (n = 30). … bus marcham to oxfordWeb4 feb. 2024 · IP3R-II Antibody (A-5) is an IgG2b κ mouse monoclonal IP3R-II antibody (also designated IP3R-II antibody or ITPR2 antibody) that detects IP3R-II of mouse, rat and human origin by WB, IP, IF and ELISA. IP3R-II Antibody (A-5) is available as the non-conjugated anti-IP3R-II antibody form, as well as multiple conjugated forms of anti-IP3R … cbs us senateWebPROTEIN SUMMARY SECTION OVERVIEW RNA DATA ANTIBODY DATA. ITPR2 INFORMATION. Proteini. Full gene name according to HGNC. Inositol 1,4,5 … busmap web appWeb29 mrt. 2024 · High expression of inositol 1,4,5-trisphosphate receptor, type 2 (ITPR2) as a novel biomarker for worse prognosis in cytogenetically normal acute myeloid leukemia. Shi JL, et al. Oncotarget, 2015 Mar 10. PMID 25779662, Free PMC Article. Genome-wide association study identifies ITPR2 as a susceptibility gene for Kashin-Beck disease in … bus map worthing