WebMar 30, 2024 · Sasso FC, Lascar N, Ascione A, Carbonara O, De Nicola L, Minutolo R, Salvatore T, Rizzo MR, Cirillo P, Paolisso G, Marfella R; NID-2 study group. Moderate-intensity statin therapy seems ineffective in primary cardiovascular prevention in patients with type 2 diabetes complicated by nephropathy. A multicenter prospective 8 years follow up study. … WebHigh intensity statin was defined as atorvastatin ≥40mg per day, rosuvastatin ≥20 mg per day, or simvastatin ≥80 mg per day, in accordance with ACC/AHA guideline (remarks: simvastatin was not considered high intensity statin after 2011) ( 4, 5 ). Patients were grouped according to the lipid management strategy into three groups.
Effects of High Intensity Statin Therapy on Steroid Hormones and ...
WebDec 15, 2024 · All patients age 21-75 with any form of CVD, or LDL-C ≥ 190, should be given high-intensity statin unless they have clinical features that might predispose them to statin toxicity (i.e., serious co-morbidities such as renal or liver dz, hx statin intolerance, ALT >3xULN, drug interactions). WebJan 30, 2024 · Individualize dose based on goals of therapy and response. Maintenance dose: 10 mg to 80 mg orally once a day. Maximum dose: 80 mg/day. Comments: Following initiation and/or upon titration, lipid levels should be evaluated within 2 to 4 weeks and dosages adjusted accordingly. shelter slough phone number
Statins: Types, Uses & Side Effects - Cleveland Clinic
WebOct 27, 2024 · Moderate- intensity statins reduce LDL-C levels by 30-49%, whereas high-intensity statins reduce LDL-C levels by ≥50%. When risk decision is uncertain, the guidelines suggest the use of 10-year ASCVD risk scoring for further risk stratification in patients aged 40-75 years with diabetes and LDL-C levels 70-189 mg/dL. Web8 hours ago · Researchers found that statins did not exacerbate muscle injury or muscle symptoms after moderate-intensity exercise."Even though muscle pain and fatigue scores were higher in symptomatic statin users at baseline, the increase in muscle symptoms after exercise was similar among the groups," said Neeltje Allard, MD, first author of the study … Webcreatinine, the high intensity statins were associated with lower amputation risk and mortality as compared to no statin [HR 0.67; 95% CI (0.63, 0.72) and HR 0.71; 95% CI … shelters long island ny