WebBrefeldin A (6) is a Penicillium brefeldianum fungal metabolite that contains a 13-membered macrocyclic lactone ring. 29 Following the initial discovery by Takatsuki and Tamura that … WebJul 11, 2024 · As an AB 5 protein toxin, Bordetella (B.) pertussis toxin (PT) consists of an enzyme subunit, the A-protomer PTS1, and five B-subunits forming a holotoxin with a pyramid-like structure, which is secreted by the bacteria [1,2,3].The B-pentamer facilitates binding to the cell surface via sialoglycoproteins that are present on most cell types …
Brefeldin A protects ricin-induced cytotoxicity in human cancer KB …
WebThe sulfated proteins fell into three groups: gp300 is not secreted and is a component of the zymogen granule membrane; pancreatic lipase (56 kDa) and a 40 kDa protein are … WebApr 16, 1999 · Brefeldin A is a small hydrophobic compound produced by toxic fungi that has dramatic effects on mammalian cells. Within minutes of brefeldin A treatment the … plus toll malaysia
Sun-Mee Kim Chonbuk National University 1 Publications 4 ...
WebBrefeldin A (BFA), an antiviral antibiotic, is a unique fungal metabolite of a 13-membered marocyclic lactone ring (Harri et al., 1963). Recently, BFA was found to cause intra- ... WebDec 5, 1988 · Brefeldin A causes disassembly of the Golgi complex and accumulation of secretory proteins in the endoplasmic reticulum The antiviral antibiotic brefeldin A (BFA) strongly inhibits the protein secretion in cultured rat hepatocytes (Misumi, Y., Misumi, Y., Miki, K., Takatsuki, A., Tamura, G., and Ikehara, Y. (1986) J. Biol. Chem. 261, 11398 … WebAug 25, 1986 · We examined the effect of brefeldin A, an antiviral antibiotic, on protein synthesis, intracellular processing, and secretion in primary culture of rat hepatocytes. … plus ykkönen.fi